Impaired grid-cell-like representations in subjects at genetic risk of Alzheimer’s disease
Institute of Cognitive Neuroscience, Ruhr University Bochum, Germany
Professor Nikolai Axmacher obtained his medical degree summa cum laude at the Humboldt University of Berlin in 2005. After working as an Epileptology reseacher at the University of Bonn until 2014, Professor Axmacher moved to the Ruhr University Bochum, where he currently runs his own group in the Department of Neuropsychology. Professor Axmacher has published more than 100 works in renowed journals and is currently a reviewer for more than 50 journals, including Science, Nature Neuroscience and Neuron. Since 2014 he also integrates the Editorial Board of Cognitive Neuroscience.
How are experiences represented in the brain and transformed into memory traces? How do these experiences shape our personality? And how is memory compromised by trauma, inner psychic conflicts and Alzheimer’s dementia? Those are the questions Professor Nikolai Axmacher and his group at the Ruhr University Bochum are trying to answer, by investigating the neural foundations of memory functions and dysfunctions using cognitive neuroscience methods, especially fMRI. With these techniques, Professor Nikolai has recently found a positive link between reduced grid cell activity, responsible for spatial navigation, and young adults at genetic risk for Alzheimer’s Disease (APOE-e4 carriers), providing new insight into this complicated disease by possibly shedding some light into its pathophysiology, as well as finding new means of predicting its occurrence. Do not miss this riveting lecture!
Location: Bochum, Germany